Merge Deluxe Free Download for free or try for a week, Tested on Windows 95/98/Me/NT/2000/XP/Vista and Mac OSX (10.4 and up) By using this site you are agreeing to the use of cookies in accordance with our Cookie Policy. Please read our Privacy Policy for more information about our use of cookies and how you can change your browser settings. Related articles Me of Spam? Do you ever receive spam e-mails that you didn't write? At MalwareTips we regularly receive spam and even Phishing e-mails. If you have any news or tips on cyber security, please let us know. Disclaimer MalwareTips.com is a non-profit resource and therefore the personnel behind MalwareTips has no commercial interest in any of the applications and tools featured on the site. If by any means this might change in the future, the new members will be made known.Follow-up assessment of MBL gene polymorphisms in an elderly Italian population. Mannose-binding lectin (MBL) is a key component of the innate immune system. The MBL pathway is the most studied pathway in relation to susceptibility to disease, and a number of single nucleotide polymorphisms (SNPs) in the promoter region and coding sequence of the gene have been identified. In our study, 40 MBL SNPs were genotyped in 305 apparently healthy subjects aged 60 years or older. Genetic data were compared with demographic data and with functional serum MBL levels. Linkage disequilibrium and haplotype analysis showed that the genetic background of the sampled population is dominated by a single haplotype (TATA). The frequency of variant alleles C and X was low, but some significant associations with variant alleles were detected. In addition, we observed a significant correlation between functional serum levels of MBL and number of promoter repeats. 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